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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX58
All Species:
23.33
Human Site:
Y518
Identified Species:
51.33
UniProt:
Q96C10
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96C10
NP_077024.2
678
76613
Y518
Q
K
M
D
Q
A
E
Y
Q
A
K
I
R
D
L
Chimpanzee
Pan troglodytes
XP_001167051
678
76609
Y518
Q
K
M
D
Q
A
E
Y
Q
A
K
I
R
D
L
Rhesus Macaque
Macaca mulatta
XP_001108799
678
76729
Y518
Q
K
M
D
Q
A
E
Y
Q
A
K
I
Q
D
L
Dog
Lupus familis
XP_850033
678
76952
Y518
Q
K
M
D
Q
A
E
Y
Q
A
K
I
R
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99J87
678
76708
F518
Q
K
M
D
P
D
E
F
K
A
K
I
R
D
L
Rat
Rattus norvegicus
NP_001092258
678
76894
F518
Q
K
M
D
P
E
E
F
K
A
K
I
Q
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509166
910
103405
L761
Q
K
W
D
E
G
E
L
V
K
R
I
H
S
L
Chicken
Gallus gallus
XP_422031
1285
144686
Y1127
Q
E
M
P
P
E
E
Y
L
N
K
I
Q
D
F
Frog
Xenopus laevis
NP_001085915
682
79226
Y521
Q
R
M
P
E
Q
E
Y
Q
K
K
I
K
E
L
Zebra Danio
Brachydanio rerio
XP_694124
738
84421
Y573
C
K
M
N
R
A
D
Y
E
K
K
I
M
E
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001176480
823
93488
K574
E
Q
E
N
D
Q
K
K
R
Q
R
E
N
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.8
84.6
N.A.
78.9
79.1
N.A.
26.9
23.7
51.1
38.8
N.A.
N.A.
N.A.
N.A.
28.6
Protein Similarity:
100
99.4
97.9
91.4
N.A.
87.6
87.7
N.A.
43.9
35.8
67.4
57.1
N.A.
N.A.
N.A.
N.A.
46.1
P-Site Identity:
100
100
93.3
100
N.A.
73.3
66.6
N.A.
40
46.6
53.3
40
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
86.6
86.6
N.A.
53.3
60
80
73.3
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
46
0
0
0
55
0
0
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
64
10
10
10
0
0
0
0
0
0
73
0
% D
% Glu:
10
10
10
0
19
19
82
0
10
0
0
10
0
19
0
% E
% Phe:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
19
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
91
0
0
0
% I
% Lys:
0
73
0
0
0
0
10
10
19
28
82
0
10
0
0
% K
% Leu:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
82
% L
% Met:
0
0
82
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
19
0
0
0
0
0
10
0
0
10
0
0
% N
% Pro:
0
0
0
19
28
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
82
10
0
0
37
19
0
0
46
10
0
0
28
0
0
% Q
% Arg:
0
10
0
0
10
0
0
0
10
0
19
0
37
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
64
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _